SMC is proud to announce that we are now working alongside the National Institute of Health and Research (NIHR) to help bring new and innovative therapies to our community.
As of April 2021 we will be carrying out high-quality research to help us improve NHS care and find better treatment options. During your consultations, your doctor may ask you to participate in a research study. Alternatively, you can ask your doctor, nurse or healthcare professional if there is a study you can take part in.
Listed below are a number of studies we are currently enrolled in.
Please note, all patient data is anonymised for our patients safety. Your participation in any study is purely voluntary.
For more information, please contact the practice.
Covid Boost Vaccine Study
The COVBOOST Study is an urgent COVID-19 study looking “to find out which vaccines against COVID-19 are most effective as a booster vaccination.
This study will be enrolling men and women over the age of 30 who received their initial prime-boost course of vaccination against COVID-19 in December 2020 or January 2021.
There is also the added pressure of delivering results in time for a potential booster vaccine program this autumn so please enroll in this study if are eligible!
Astra Zeneca Vaccine Trial
As you have now received your first AstraZeneca COVID-19 vaccine we would like to invite you to participate in a study run by the Drug Safety Research Unit in Southampton which is monitoring the safety of this vaccine.
If you are interested and would like more information, please visit goto.dsru.org/covid or call 0800 619 6222.
Memory (Active Brains Study)
A new website called ‘Active Brains’ aims to help older adults to look after their brain and body health to prevent cognitive decline. The website supports older adults to make simple behavioural changes such as increasing physical activity, playing brain training games and finding ways to eat more healthily. This study will trial the effectiveness and cost effectiveness of ‘Active Brains’.
Depression (PROMDEP RCT)
The study will look at whether giving personal feedback to people being treated for depression might help them get better more quickly. This will be done by using patient reported outcome measures ('PROMs') which involve patients completing questionnaires to record their symptoms of depression and feeding back these results to the practitioners looking after them.
The study is ‘investigating the effectiveness and cost-effectiveness of assessing primary care patients with depression or low mood soon after diagnosis and again at follow-up 10-35 days later, using the PHQ-9 questionnaire combined with patient and practitioner feedback and guidance on treatment.’
Depression (REDUCE Study)
The study will look at whether giving personal feedback to people being treated for depression might help them get better more quickly. This will be done by using patient reported outcome measures ('PROMs') which involve patients completing questionnaires to record their symptoms of depression and feeding back these results to the practitioners looking after them. The study is ‘investigating the effectiveness and cost-effectiveness of assessing primary care patients with depression or low mood soon after diagnosis and again at follow-up 10-35 days later, using the PHQ-9 questionnaire combined with patient and practitioner feedback and guidance on treatment.’
Covid-19 (RTO- Covid-19 Study)
Southampton University would like to understand what people have done to avoid catching Covid-19, and whether it worked. If people became ill with Covid-19, we’d like to find out what people tried to treat the symptoms. They would also want to know how the illness affected them in the short and longer term.
This survey is open to EVERYONE over 16 years old, whether or not you have been been ill or not.
Whether you have had COVID or not, you can help researchers understand how to beat the virus by completing a survey run by the University of Southampton. You could win one of 62 vouchers (£5 to £500).
If you are interested, please click here for more information.
Depression (ALPHA Stim-D trial)
The University of Nottingham would like to find an alternative way to help people with depression who may prefer not to use medication or have not benefitted from anti-depressant medication or psychological treatment.
They are testing the effectiveness of a clinically proven medical device called Alpha-Stim AID for the treatment of depression. The Alpha-Stim-D trial will them decide if the device should be made freely available through the NHS.
What would taking part involve?
- An interview to see if you are eligible to take part
- Using a device daily for 60 minutes for 8 weeks in your home
- Completing some brief questionnaires over 4 months
- You will receive a £10 gift voucher for completing the final questionnaire
If you would like to hear more, please contact the practice.
Diabetes (ASPIRE-DNA Clinical Trial)
Are you at risk of developing type 2 diabetes?
Do you think you may be pre-diabetic?
Are you over 18?
You may be eligible for our research study. ASPIRE-DNA is a clinical trial to assess the impact of a DNA-based diet on reducing the risk of type 2 diabetes. Using DnaNudge technology, participants will receive a genetic report and an app to help make healthier food shopping choices based on their DNA. If you’re interested, please contact the clinical trial team using the QR code listed across:
Covid 19 (Principle Study)
The PRINCIPLE Trial is trying to find new treatments for COVID-19 that that can be used in the community. We hope to find treatments that help people recover quicker without needing to be admitted to hospital.
To take part, you need to be experiencing symptoms that are likely to be caused by a COVID-19 infection, for fewer than 15 days:
- a new continuous cough
- or a high temperature
- or a loss of, or change in, normal sense of taste or smell
- You have had a positive test for SARS-Co-V2 infection which was taken fewer than 15 days ago, AND are unwell with symptoms of COVID-19. These symptoms may include, but are not limited to, shortness of breath, general feeling of being unwell, muscle pain, diarrhoea, vomiting, fever and cough, and you must have had them for fewer than 15 days.
Also, to join the trial, you need to be either
- Aged 65 and over
- Aged 18-64, and experiencing shortness of breath* as part of COVID-19 illness
- Aged 18-64 with any of the following underlying health conditions:
a) Known weakened immune system due to a serious illness or medication (e.g. chemotherapy);
b) Known heart disease and/or a diagnosis of high blood pressure
c) Known chronic lung disease (e.g. asthma)
d) Known diabetes
e) Known mild hepatic impairment;
f) Known stroke or neurological problem;
g) Self-report obesity or body mass index ≥35 kg/m2 *Shortness of breath can make it hard to breathe deeply and you may feel winded or as if you can’t get enough air into your lungs. Unlike many other conditions that can cause shortness of breath, this symptom can persist and quickly escalate in people with COVID-19.
To take part in the study, please click here.
Clinical Practice Research Datalink and RCGP
We are part of Clinical Practice Research Datalink which means that we contribute de-identified data to CPRD (Clinical Practice Research Datalink) for public health research. CPRD is a real-world research service supporting retrospective and prospective public health and clinical studies and is jointly sponsored by the Medicines and Healthcare products Regulatory Agency and the National Institute for Health Research (NIHR), as part of the Department of Health and Social Care.
Individual patients cannot be identified from this information (click here for more information), but you are able to opt out if you prefer. Protecting the confidentiality of patient data is paramount, and only anonymised patient data is provided to researchers.
We are part of the Royal College of General Practitioners (RCGP) Research Surveillance Centre (RSC) which means that we contribute de-identified data to the RSC for public health research. The RSC is an active research and surveillance unit that collects and monitors data, in particular Influenza, from practices across England. Individual patients cannot be identified from this information (click here for more information).
Living with Long Term Conditions
The University of Southampton is conducting a Study to validate the scale of 'Living with a Chronic Illness' in an English-speaking population. The medical conditions they are currently evaluating are:
- Chronic Obstructive Pulmonary Disease
- Chronic Heart Disease
- Parkinson's Disease
- Chronic Kidney Disease
- Diabetes type II
The study involves a number of brief questionnaires which the patients would need to complete. To reward the patients for their time, the University of Southampton will give each patient a £10 amazon gift card.